????? ??? ?? ?? ?? ? ?? ??? ?? ???? , ?? ??? ????? ??? ?? ?? ?? ????? ??? ?? ?? ?? ???? ?? ??? ?? ??? ??? ?? ??? ? ??? ??? ?? ????. ?? ?? ????? ?? ??? ?? ??? ??? ???? ????.  Individuals with PNH are at increased threat of developing most cancers in blood-forming cells (leukemia). In s